We use a combination of cellular biology, biochemistry, biophysics, and structural biology (cryo-electron microscopy and X-ray crystallography) to understand the atomic-resolution mechanisms by which various pathogens evade the immune system, recognize the cellular host, acquire access to the cell, modify the cellular environment, and replicate.
 
Due to the competitive nature of science and current funding levels we refrain from discussing the specifics of our research till funding for each project has been acquired.
 
Below are a number of images that summarize the PI's prior research. The ongoing research will be similar in scope yet more medically relevant. Feel free to watch the slide show to get a better idea of our research techniques and strategies. The strength of the laboratory is structural biology.

Prior Research Examples

resources

Available to the lab

The facilities below are fully accessible to members of the laboratory

and will be heavily used throughout the research

New York Structural Biology Center

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Advanced Science Research Center

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CUNY High Performance Comp. Center

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Institute for Macromolecular Assemblies

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